In an evaluation of 49 top-selling brand-name drugs, 28 of the drugs available since 2012 saw an increase in insurer and out-of-pocket costs of more than 50 percent by 2017 and 16 more than doubled in price, according to a study reported Friday in JAMA Network Open. The study examined pharmacy claims data for more than 35 million people with private pharmaceutical insurance. 
 

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