NIH launches phase 3 investigational trials for pair of monoclonal antibody therapies for COVID-19

Dec 18, 2020 - 02:36 PM
NIH-cancer-deaths

The National Institutes of Health yesterday announced enrollment in phase 3 of the clinical trial of two disparate therapies. This trial is specifically looking at the safety and effectiveness of the therapeutics in people hospitalized with moderate COVID-19 symptoms.

The two approaches being tested are the use of VIR-7831, a monoclonal antibody developed through a partnership between GlaxoSmithKline and Vir Biotechnology, Inc., and a combination of neutralizing monoclonal antibodies, BRII-196 and BRII-198, that are manufactured by Brii Biosciences.

Initially, approximately 450 people will be enrolled, with a third of participants receiving a placebo, a third receiving VIR-7831 and a third getting the combination of Brii therapeutics. It the trials appear successful, an additional 700 people hospitalized with COVID-19 will be enrolled. 

Related News Articles

Headline
CDC report finds COVID-19 vaccine for children reduced chances of ED, urgent care visits
The Centers for Disease Control and Prevention Dec. 11 released a report that found last year’s version of the COVID-19 vaccine was 76% effective in preventing…
Headline
ACIP recommends patients consult their provider for COVID-19 vaccine
The Advisory Committee on Immunization Practices Sept. 19 recommended that patients should consult their health care provider if they want to receive a COVID-…
Headline
COVID-19 vaccination approved for older adults and high-risk, younger children
 The Food and Drug Administration July 10 approved Moderna’s Spikevax COVID-19 vaccine for children under 12 with at least one underlying condition that…
Headline
RFK Jr. says CDC will no longer recommend COVID-19 vaccine for healthy children, pregnant women
Department of Health and Human Services Secretary Robert F. Kennedy Jr. May 27 announced in a post on X that the Centers for Disease Control and Prevention…
Headline
FDA to limit COVID-19 vaccine to people over 65, others at high risk for serious illness
Leaders of the Food and Drug Administration May 20 announced new guidelines for administering the COVID-19 vaccine in a paper published by the New England…
Headline
Senate Finance Committee advances RFK Jr. nomination for HHS secretary
The Senate Finance Committee Feb. 4 voted 14-13 to advance Robert F. Kennedy Jr.’s nomination for secretary of the Department of Health and Human Services. A…