The number of Americans with uncorrectable vision impairment could double by 2050 unless efforts are made to slow the progression and severity of many common age-related eye diseases and conditions, according to a report released today by the National Academies of Sciences, Engineering, and Medicine. The report recommends that the Secretary of Health and Human Services issue a call to action to eliminate correctable and avoidable vision impairment by 2030; delay the onset and progression of unavoidable chronic eye diseases and conditions; minimize the impact of chronic vision impairment; and achieve eye and vision health equity by improving care in underserved populations. It also calls for a public awareness campaign and surveillance system for eye and vision health; common research agenda and coordinated research and demonstration grant programs; single set of evidence-based clinical and rehabilitation practice guidelines; and state and local partnerships to align public health and clinical practice objectives and strategies; among other actions.