The Agency for Healthcare Research and Quality has released a map showing state trends and variation in opioid-related hospital stays between 2009 and 2014. According to a recent AHRQ report, opioid-related hospital stays increased 75% for women and 55% for men between 2005 and 2014, while opioid-related emergency department visits doubled for both sexes. In 2015, mental health and substance use disorders together were the leading cause of disease burden in the United States, surpassing cancer and cardiovascular disease, according to an infographic published last week in the Journal of the American Medical Association.