The Health Resources and Services Administration has provided an update on its new 340B Office of Pharmacy Affairs Information System, which includes a new registration system and a new secure pricing system. HRSA said the registration component of the new 340B OPAIS will be released in mid-September and the pricing system will be released at a later date. As of Aug. 15, the current 340B database is offline and unavailable. At this time, 340B covered entities are not able to submit change requests or terminations. However, external users can continue to verify covered entity participation, manufacturer participation and contract pharmacy locations in the 340B program. HRSA plans to provide more information and updates on the move to the OPAIS on its website. Questions on registration can be directed to the 340B Prime Vendor Program at (888) 340-2787.