NIH launches phase 3 investigational trials for pair of monoclonal antibody therapies for COVID-19

Dec 18, 2020 - 02:36 PM
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The National Institutes of Health yesterday announced enrollment in phase 3 of the clinical trial of two disparate therapies. This trial is specifically looking at the safety and effectiveness of the therapeutics in people hospitalized with moderate COVID-19 symptoms.

The two approaches being tested are the use of VIR-7831, a monoclonal antibody developed through a partnership between GlaxoSmithKline and Vir Biotechnology, Inc., and a combination of neutralizing monoclonal antibodies, BRII-196 and BRII-198, that are manufactured by Brii Biosciences.

Initially, approximately 450 people will be enrolled, with a third of participants receiving a placebo, a third receiving VIR-7831 and a third getting the combination of Brii therapeutics. It the trials appear successful, an additional 700 people hospitalized with COVID-19 will be enrolled. 

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