List prices for branded drugs in U.S. rose 159% over 11 years

List prices for branded pharmaceutical products in the United States increased 159% between 2007 and 2018, an average of 9.1% per year, according to a study reported this week in JAMA. List prices represent the manufacturers’ price to wholesalers or direct purchasers, but do not account for discounts. Net prices for branded pharmaceutical products, which represent per unit revenue after all discounts and manufacturer concessions, increased 60% over the period, or an average 4.5% per year, the study found.