A new report from the National Academies of Sciences, Engineering, and Medicine examines the advantages, limitations and status of certain COVID-19 diagnostic tests, including reverse transcription polymerase chain reaction tests, point-of-care tests, and next generation sequencing tests.

The report also identifies situations in which split-pool testing (testing pools of samples, then splitting the pool and testing again) and wastewater surveillance (a method for testing water containing human waste to detect symptomatic and asymptomatic individuals) can provide advantages beyond individual diagnostic testing methods.

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