Navigating Patient Risk and Engagement with Genomic Precision

AHA Knowledge Exchange Navigating Patient Risk and Engagement with Genomic Precision
AHA Knowledge Exchange | Navigating Patient Risk and Engagement with Genomic Precision

AHA Knowledge Exchange

Delivering personalized, affordable care while prioritizing population health and health equity

Understanding what makes each individual unique is key to achieving optimal health and engaging with patients for personalized, high-quality health care outcomes. Major health systems have been increasing patients’ access to genomics to holistically understand their predisposition to certain diseases, tailor care plans and provide proactive and preventive care rather than treating disease after it manifests. Through large-scale screening, organizations are developing the capability of identifying potential health risks that may be disproportionately affecting ethnically diverse individuals in their community to facilitate the development of proactive health initiatives. This knowledge exchange explores innovative strategies and applications of genomics data to enhance the precision of patient-risk stratification for a more preventive and individualized approach to care.

Sponsored by: Helix Logo

5 steps health system leaders are taking in their genomics strategy to empower patients and health care providers

  • Investigate how to get on the front edge of integrating patients’ genomic information seamlessly into the standard of care.
  • Examine health systemwide programs for population health screenings to take preemptive measures aimed at delaying, mitigating or averting life-threatening conditions.
  • Pilot use cases in areas with evidence of actionable benefit: familial hypercholesterolemia, hereditary breast and ovarian cancers, Lynch syndrome [the most common form of hereditary colorectal cancer], pharmacogenomics for anxiety and depression.
  • Explore electronic health record (EHR) tools for data aggregation and reporting to help improve clinical workflows and create data strategies that may allow for opportunity assessments.
  • Engender trust and embed genomics into the health equity team with a community advisory board to build trust, to focus on research and bring novel discovery to Black, Indigenous and people of color. Be explicit with consent that patients own their data, have access to it and it is portable.


Nwando Anyaoku

Nwando Anyaoku, M.D., MPH, MBA

Chief health equity and clinical innovation officer


Nick Bennett

Nick Bennett, PharmD, BCPS, BCIDP

Manager, Antimicrobial and Diagnostic Advisement Program

Saint Luke’s (West Region), BJC Health System

Casey Granack

Casey Granack, MHA, PCMH CCE

Manager, innovations


Cassie Hajek

Cassie Hajek, M.D., FACP, FACMG

Medical director


Manoja Lecamwasam

Manoja Lecamwasam, PhD, MBA

System vice president, intellectual property and strategic life sciences

CommonSpirit Health

Craig Newman

Craig Newman

Senior vice president, health systems and strategic partnerships


Balazs Zsenits

Balazs Zsenits, M.D.

Chief medical information officer and senior vice president

Rochester Regional Health

Suzanna Hoppszallern

Suzanna Hoppszallern

Senior editor, Center for Health Innovation

American Hospital Association


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